Guest post by Dr. Felice Gersh. Just thinking “acne” makes my stomach churn….it is one of the most hated of all the PCOS symptoms. Acne affects a large percentage of women with PCOS and is something you simply cannot ignore. Systemic isotretinoin remains the most efficacious treatment for severe acne as well as many cases of more moderate disease that are unresponsive to other treatment modalities. This is my story how I cleared my acne just by my diet and by balancing my hormones out. I hope I can help some of you. Sending lots of love to you guys 💕 Isotretinoin, 20 and PCOS. Hello, i am 20 year old having pcos. Recently my mom got me isotroin-20 since she met a lot of people whose acne was benefited by it. It’s important to know that even the best PCOS acne treatment will do little without a good skin care routine. Make sure you: Wash your face twice a day. There have been a number of women in the PCOS Diet Support Community who are struggling with Acne, in spite of following a good PCOS diet and taking their supplements. I don't know about PCOS specifically, but it has been linked to permanent reproductive damage and infertility in both sexes. I would say, taking that into consideration, that it's most certainly a possibility. It was also suggested that if I saw no improvements then I could try spironolactone (a powerful anti-androgen) or isotretinoin (marketed as Accutane). The problem with both of these treatments is that they produce a lot of nasty effects in the body. They also don’t really solve the root cause of the acne. Although I see PCOS acne improvements from the pill, antibiotics, and spironolactone, a. Hi there, I'm 37 with PCOS & bad acne. When I was 15 I took Roaccutane, as it's known in Australia. After being on very high dosage for 6 months, it cleared my skin for a few years. Our acne is hormonal and with PCOS, we produce too much testosterone/androgens and that is too strong. My acne returned. My acne returned. I am not trying Yazmin to help with the body hair/acne and hoping for the best.